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La stabilit du compos a t dtermine laide dune gamme de solvants. Il sagit dun agent antifongique largement utilis pour le traitement des pellicules. Chat privately with our registered medical specialists to connect directly with verified doctors. This work aimed to evaluate the antifungal activity of piroctone olamine in the treatment of intra-abdominal candidiasis in an experimental model using Swiss mice. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating. Piroctone Olamine is an antifungal medication. It also needs to offer excellent cosmetic and hair conditioning benefits at the same time. Bras. the contents by NLM or the National Institutes of Health. Reboot Scalp Tonic maintains beautiful hair from the roots of a healthy scalp. WebSeborin Hair Tonic by Schwarzkopf effectively fights itchy scalp and ensures dandruff-free hair and a scalp that feels good with Octopirox. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Parfum (Fragrance), Pentylene Glycol, Chlorphenesin, Glycerin, Caffeine, Hydrolyzed Wheat Protein, Piroctone Olamine, Triticum Vulgaire (Wheat) Bran Extract, Phenoxyethanol, Sodium Benzoate, Pisum Sativum (Pea) Extract, 2011). The susceptibility testing followed the broth microdilution method, in accordance with the standards published in Document M27-A3 from the Clinical and Laboratory Standards Institute. 1983) to confirm the species involved in the infection. Piroctone Olamine: View Uses, Side Effects and Medicines We used the immunosuppression protocol from Medeiros et al. Piroctone olamine Le point de fusion a t dtermin laide du calorimtre balayage diffrentiel (Differential Scanning Calorimetry, DSC) Q2000 (TA Instruments, tats-Unis). Piroctone Olamine (Kopirox) is an effective, practically nontoxic antidandruff active ingredient which is particularly suitable for the manufacture of antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action. The antifungal drugs most commonly used to treat this type of invasive mycosis are amphotericin B, fluconazole and echinocandins (Bassetti et al. Iliopoulos F, Sil BC, Moore DJ, Lucas RA, Lane ME. government site. 2021 Nov;43 Suppl 1:S14-S25. Conclusion: WebSeborin Hair Tonic by Schwarzkopf effectively fights itchy scalp and ensures dandruff-free hair and a scalp that feels good with Octopirox. Web1. Before each application, wash the affected area with soap and water and dry well.. Several in vitro studies with a new medical device (Myfungar) containing 0.5% of piroctone olamine (CAS 68890-66-4, octopirox) in a hydroxypropyl chitosan hydroalcoholic solution were performed. The experiment was performed in two steps: (1) in the first, the treated and untreated animals were observed for mortality for 14days, (2) in the second stage, the animals were sacrificed after 7days of treatment for the mycological diagnosis. Know Your Environment. The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Piroctone olamine decreases sebum production in the scalp. This evaluation took place 14days after infection with yeast. National Library of Medicine Low aquatic toxicity (no labeling required), Appearance: White to faintly yellowish-white 1), 1-8 (2021). The cream containing climbazole/piroctone olamine (C/P cream) (Sensibio DS+; Bioderma Laboratoire Dermatologique, Lyon, France) tested in this study is a cosmetic product containing piroctone olamine and climbazole. Dermatol Clin. Copyright Clariant 2023. Dandruff and its more severe related condition, seborrheic dermatitis affects a high proportion of the population at some point in their life. The difference in FG scoring between the control group and the treatment groups (PO and AMB) was statistically significant (P<0.05). It is a component of many cosmetic products such as anti-dandruff shampoo and hair rinses for scaly and irritated skin. Rebolledo M, Sarria J. Intra-abdominal fungal infections. piroctone olamine da Engenharia, s/n, Cidade Universitria, Recife, PE CEP 50740-550 Brazil. Use restrictions (moderate) SYNONYMS. CONTENT DETAILS Written By Dr. Radhika Dua MDS, BDS Reviewed By Dr. Shilpa Garcha MD (Pharmacology), MBBS Last updated 13 Mar 2020 | 12:30 PM (UTC) We provide you with authentic, trustworthy and revelant information Want to know more Available Medicine for Piroctone Olamine Expert advice for Piroctone Olamine These microorganisms split parts of the sebum of the capillitium lipolytically into free fatty acids. WebThis hair & scalp tonic rebalances dry and oil scalps and revitalises the hair, thanks to Piroctone Olamine, which helps to regulate sebum for healthy and less breakable hair. European Commission. WebThe Status of Over-the-Counter (OTC) Rulemakings contains the citation number of the Federal Register notices organized by therapeutic category subtopics. Piroctone olamine - Wikipedia 325 325. All rights reserved. Piroctone Olamine 2021 Society of Cosmetic Scientists and Societe Francaise de Cosmetologie. [1] Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone. EWG Department of Mycology, Federal University of Pernambuco (UFPE), Av. Piroctone Olamine Shampoo. Curr. To evaluate the therapeutic efficacy of PO, fungal growth (FG) in culture media was scored according Leal et al. Fungi can infect virtually any organ or structure in the abdomen. All rights reserved. Int J Cosmet Sci. Dermatol. Designed specifically to treat seborrheic dermatitis and dry scalp, Piroctone Olamine offers additional benefits: it is environmentally friendly, multifunctional (doubles as preserving agent), and flexible for various cosmetic formats. The Salicylic Acid will help exfoliate existing dandruff build up while the Piroctone Olamine is designed to prevent any new outbreaks. A replenishing active ingredient that reduces grease on the scalp thanks to its targeted action on the pores. In addition to this antifungal activity, the drug also has good activity against gram-positive and gram-negative bacteria. Get all the latest news from ALFAPARF MILANO PROFESSIONAL. Invasive candidiasis is a frequent and life-threatening complication in critically ill surgical patients (Tissot et al. How to Use Piroctone Olamine for Hair Care. An approach to decrease hair shedding by reducing scalp stratum corneum oxidation via a combination of antioxidant and barrier-enhancing technologies has been previously demonstrated. Energizing Tonic | Alfaparf Milano Professional Toutefois, les chantillons situs dans la partie infrieure de la courbe dtalonnage ont montr des degrs infrieurs de prcision et dexactitude. Leave-in products: 0.05 - 0.1%. Webalcohol denat.,aqua (water),butylene glycol,parfum (fragrance),glycerin,menthyl lactate,peg-40 hydrogenated castor oil,piroctone olamine,eruca sativa leaf extract,juglans regia piroctone olamine Piroctone olamine is an ethanolamine salt extracted from hydroxamic acid derivative piroctone. Best Piroctone Olamine Shampoos Le coefficient de distribution (logD(Octanol/PBS) ) et le coefficient de partage (log Poctanol/eau , ou log Poe ) ont t dtermins dans le tampon phosphate salin (phosphate buffered saline, PBS) et dans leau dsionise (deionised, DI) laide de la mthode par agitation en flacon. Piroctone Olamine But piroctone olamine can be a solution for dandruff and other major hair problems. Antifungal activity of the piroctone olamine in If accidental contact occurs, rinse immediately with water. Piroctone Olamine Les solutions ont t conserves et agites tout au long de lexprience une temprature de 32C 1C. HHS Vulnerability Disclosure, Help antioxidant; hair growth; hair loss; hair shedding; hair treatment; scalp; skin barrier. An. PMC Got a health query? According to Tissot et al. (adsbygoogle = window.adsbygoogle || []).push({}); About Author Bassetti M, Marchetti M, Chakrabarti A, Colizza S, Montero JG, Kett DH, et al. Evaluation and Licensing Division. 100 ml Shampoo in 1 Bottle. The distribution coefficient (logD(O/PBS) ) and partition coefficient (log Po/w ) was determined in phosphate-buffered saline (PBS) AND deionized (DI) water using the shake flask method. Kim Y, Alpmann P, Blaum-Feder S, Krmer S, Endo T, Lu D, Carson D, Schmidt-Wolf IGH. Piroctone Olamine Canadian Environmental Protection Act (CEPA) Environmental Registry. WebAn approach to decrease hair shedding by reducing scalp stratum corneum oxidation via a combination of antioxidant and barrier-enhancing technologies has been previously demonstrated. 2011 Jun;33(3):276-82. doi: 10.1111/j.1468-2494.2010.00623.x. Pastore MN, Kalia YN, Horstmann M, Roberts MS. Transdermal patches: history, development and pharmacology. The antimicrobial compound piroctone olamine is known to be effective in vitro against pathogenic fungi such as Candida species, Aspergillus fumigatus and Toutes les expriences ont t ralises temprature ambiante. Research Shows Reducing Scalp Stress Improves Hair Anchoring The site is secure. The site is secure. Bethesda, MD 20894, Web Policies WebSafe active ingredient Piroctone Olamine, an established cosmetics preservative, is proven also to be effective at controlling microorganisms responsible for flaking and irritation, reducing dandruff and scalp itch. Would you like email updates of new search results? la production de pellicules et la maladie plus grave qui y est apparente, la dermatite sborrhique, touchent une grande partie des personnes un moment donn de leur vie. CONTENT DETAILS Written By Dr. Radhika Dua MDS, BDS Reviewed By Dr. Shilpa Garcha MD (Pharmacology), MBBS Last updated 13 Mar 2020 | 12:30 PM It is often used as an antidandruff agent with shampoo and etc. In this study, the efficacy of a shampoo containing 0.5% piroctone olamine and 0.45% climbazole (shampoo 1) was compared with a widely available commercial shampoo containing 1% zinc pyrithione (shampoo 2). Please enable it to take advantage of the complete set of features! In the group treated with AMB, the fungus was isolated from the liver (three animals) and spleen (one animal). Dupont H, Paugam-Burtz C, Muller-Serieys C, Fierobe L, Chosidow D, Marmuse JP, et al. Log in or register to ClariHub for our full set of ingredient documentation, formulations and more resources! Treatment of this type of infection is a major challenge because of the difficulty of diagnosis, limited number of antifungals and emergence of strains resistant to the available drugs (Quintero 2010; Yu et al. Every product and ingredient in Skin Deep gets a two-part score one for hazard and one for data availability. Higuchi T. Physical chemical analysis of percutaneous absorption process from creams and ointments. Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff. Kopirox is known for its bacterio-static and fungi-static properties specifically working against Pityrosporum ovale, which lives on the skin and is associated with dandruff and other manifestations of flaking on the face and scalp. Stock: 200 Kg. The effect of piroctone olamine on reproduction of male and female rats. Tonic Do not rinse off. For dandruff free hair with Octopirox Against itchy head. WebPiroctone Olamine. 2013; Dupont et al. Enhanced piroctone olamine retention from shampoo for superior anti-dandruff efficacy. An official website of the United States government. International Journal of Cosmetic Science published by John Wiley & Sons Ltd on behalf of Society of Cosmetic Scientists and Societe Francaise de Cosmetologie. FMMC, SCN, SFPJ and VKAS performed the antifungal activity of piroctone olamine in vitro and in vivo against Candida clinical isolates. Protect Your Health. It has fungicidal and sporicidal activity in vitro . Record Status. PIROCTONE OLAMINE The https:// ensures that you are connecting to the official website and that any information you provide is encrypted 2013. Webpiroctone olamine, disodium phosphate, zinc gluconate, magnesium aspartate, plankton extract, biosaccharide gum-1, limonene, biotin, paullinia cupana seed extract, sodium Yu L, Ling G, Deng X, Jin J, Jin Q, Guo N. http://creativecommons.org/licenses/by/4.0/. Data regarding the fungal growth and mortality were analyzed statistically by Students t test and analysis of variance (ANOVA), with level of significance set at P<0.05. Intra-abdominal fungal infections can be divided in two groups according to their clinical presentation: localized, following surgery, trauma, or placement of foreign device; and disseminated, in critical ill or immunocompromised patients. Piroctone Olamine can be used in hair care products, such as shampoos and conditioners, to help control dandruff Inclusion in an NLM database does not imply endorsement of, or agreement with, In the first stage of the experiment, the in vivo mortality rate was six dead animals in the untreated group and three dead animals in the groups treated with PO and AMB. The concentration can be reduced even further for preparations that remain on the hair or the scalp. Unable to load your collection due to an error, Unable to load your delegates due to an error. 3-O-ethyl-l-ascorbic acid: Characterisation and investigation of single solvent systems for delivery to the skin. 43(Suppl. Octopirox - Clariant- Technical Datasheet - SpecialChem Sur les 4 jours, lOPX a montr une stabilit dans lthanol et le PG, tandis quil a diminu de manire notable dans le PBS et leau dsionise une temprature de 32C 1C. Registration Dossier - ECHA A. Tosti, J. R. Schwartz. Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24-week randomized, double-blind, placebo-controlled clinical trial. Standards for Cosmetics. The antidandruff efficacy of a shampoo containing piroctone .. rebalance the scalp. Fresh effect. Piroctone Olamine 2013 Jan;31(1):173-8. doi: 10.1016/j.det.2012.08.004. Apply it as per the dose and duration advised by your doctor. Piroctone Olamine is safe for use when added under the recommended percentage usage - 0.1% for rinse-off products and 0.5% for leave-on products. WebAn approach to decrease hair shedding by reducing scalp stratum corneum oxidation via a combination of antioxidant and barrier-enhancing technologies has been previously demonstrated. 2012;34(6):496-501. Please use the contact form bellow for moreinformation or any questions about Octopirox. Studies with mice, rats and dogs have shown that the PO has low toxicity. Octopirox - Clariant Ltd. It is preferred by formulators across the world because of its good solubility and safety parameters. The minimum inhibitory concentration (MIC) was the lowest concentration capable of inhibiting visible growth of the isolates tested against the respective control well. J. Cosmet. La solubilit a t dtermine de manire exprimentale. It is active against dermatophytes, yeasts and non-dermatophyte molds. 2011). Sur la base des expriences avec le DSC, le point de fusion a t observ une temprature initiale de 132,4C. For dandruff free hair with Octopirox Against itchy head. Read on to know the benefits and side effects of piroctone olamine. Octopirox is compatible with most surfactants, additives and active ingredients used in cosmetic formulations. Piroctone Olamine HHS Vulnerability Disclosure, Help The chemical formula of Piroctone Olamine is C. Piroctone Olamine is quite beneficial in maintaining cosmetic and personal care products. Accessibility It is generally considered safe, non-irritating and non-allergenic. CAS: 68890-66-4. Overview. -Glucan antigenemia anticipates diagnosis of blood culture-negative intraabdominal candidiasis. Click on the product link below to learn more. Coffee Hair & Scalp Tonic 120ml The mycological diagnosis was made by collecting the liver, spleen and kidneys. formula: C16H30N2O3 Piroctone Olamine has a petrochemical origin. Objective: The in vivo antifungal activity of PO and AMB in the experimental intra-abdominal candidiasis can be seen in Table2. A study by NCBI anti-dandruff shampoos with Piroctone olamine, effective in treating hair shedding and thinning. It has low aquatic toxicity and broad-spectrum preservation. Anti-acne with Piroctone Olamine. The plates were incubated at 37C for up to 72h. Grown yeast colonies were purified, isolated and identified through morphological and physiological characteristics (Barnett et al. MTHODES: une mthode de chromatographie liquide haute performance (CLHP) a t dveloppe et valide pour lanalyse de lOPX. All Rights Reserved. 2023 The Authors. Allgood GS, Miller JM, Schardein JL. For comparison, a group of animals (n=6) was treated with amphotericin B (0.5mg/Kg). The Skin Deep scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern. MeSH crystalline powder. Bengaluru. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. In the in vitro susceptibility testing, we found that the clinical isolates of Candida spp. piroctone olamine Sci. These solutions were kept and stirred throughout the experiment at 32 1C, and aliquots were taken at 24, 48 and 96 h. Results: NLM (National Library of Medicine). Role of scalp health in achieving optimal hair growth and retention. WebHome INCI Directory Share PIROCTONE OLAMINE Piroctone Olamine is a synthetic ingredient that is used mainly as a preservative in personal care and cosmetic products. PMC FOIA It works by penetrating the cell membrane of the fungi to interfere with their energy metabolism and oxygen uptake. The .gov means its official. We do not process requests for Schedule X and habit forming drugs. Schmidt-Rose T, Braren S, Flster H, Hillemann T, Oltrogge B, Philipp P, Weets G, Fey S. Int J Cosmet Sci. Chem/IUPAC Name: 1-Hydroxy-4-methyl-6- (2,4,4-trimethylpentyl)pyridin-2 (1H)-one, compound with 2-aminoethanol (1:1) EINECS/ELINCS No: 272-574-2. 43(Suppl. Get free medicine home delivery in over 1800 cities across India. The https:// ensures that you are connecting to the The concentrations of piroctone olamine (PO) ranged from 0.0625 to 32g/mL. It is an environmental friendly and multifunctional (doubles as a preserving agent). Octopirox is one of the most efficient anti-dandruff actives available on the market today. Enjoy free home sample collection, view reports online and consult a doctor online for free. All labs listed on the platform are accredited, Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant. WebPiroctone Olamine is an antidandruff agent used in antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action. La Roche Posay is a combination shampoo, combining both Piroctone Olamine and Salicylic Acid. EC / List no. Le LogD a t dtermin 1,84. IMAGE SOURCE: PubChem. Eur J Pharm Sci. Energizing maintenance treatment: we recommend applying the tonic 4 times a week for at least 8 weeks. In the untreated group it was possible to isolate the fungus from the liver (all animals), spleen (three animals) and kidneys (three animals). WebMethods: Female subjects with self-perceived hair thinning participated in an 8-week, double-blind, placebo-controlled, randomized clinical study to evaluate either a piroctone olamine (PO) containing shampoo or a PO containing leave on treatment, each relative to their corresponding placebo formulation Too many periods. Please choose one of the available product configurations: Based on your current location and language, you might be interested in this file: There are no files available for this product. There is only a modest volume of research. Octopirox has been successfully used for over 30 years for its good compatibility, its antimicrobial functionality and its long shelf life. Piroctone Olamine A successful anti-dandruff shampoo not only has to provide superior anti-dandruff relief to ensure patient compliance. For quality control, the strains C. parapsilosis ATCC 22019 and C. krusei ATCC 6528 were included as quality control, as recommended by (CLSI 2008). Disclaimer. 2011; Allgood et al. It is known that this agent has the ability to penetrate the cell membrane and form complexes with irons (Fe2+ e Fe3+), inhibiting energy metabolism in mitochondria of pathogenic fungi (Kim et al. Piroctone Olamine 561672/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom. The EWG VERIFIED mark means a product meets EWGs strictest criteria for transparency and health. Results: Expert Opin Drug Deliv. Antifungal activity of the naphthoquinone beta lapachone against disseminated infection whith, Quintero CHG. Resistencia de levaduras del gnero. Other Concerns. Piroctone olamine, also known as Octopirox (OPX) is the monoethanolamine salt of piroctone and is an antifungal agent widely used for the Schmidt-Rose T, Braren S, Flster H, Hillemann T, Oltrogge B, Philipp P, Weets G, Fey S. Int J Cosmet Sci. Piroctone Olamine Product Function Antidandruff Agents Chemical Type Heterocyclic Compounds Applications Shampoo Hair Conditioner Hair Styling It is extremely easy to formulate, enabling stable formulations with no effort. 29, 26-42 (2001). Unauthorized use of these marks is strictly prohibited. La Roche-Posay Kerium Anti-Dandruff Shampoo. Healthline 2015 as follows: 0no fungal growth in culture medium; and 1fungal growth in culture medium. Tonic EC (Environment Canada). As it effectively works on dandruff and fungal infections, naturally, your hair loss decreases over time. A4V5C6R9FB. MOQ: 1Kg. Epub 2012 Oct 2. Dandruff can be a real trouble maker and can cost you, your precious locks. LOPX prsentait la solubilit la plus faible dans lisosorbide de dimthyle (9,9 mg.mL1 ), le LabrafacTM (3,6 mg mL1 ) et lisostarate disostaryle (0,5 mg mL1 ). Piroctone olamine (INN; also known as piroctone ethanolamine;) is a compound sometimes used in the treatment of fungal infections. The https:// ensures that you are connecting to the Piroctone Olamine It is important to recognize these infections early since serious complications, such as intestinal obstruction, bleeding, perforation, peritonitis, sepsis and death, can occur (Rebolledo and Sarria 2013). Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data. Use an anti-dandruff shampoo containing piroctone olamine to fight dandruff. WebProducts with Piroctone Olamine. Treatment of Raynaud's diseases with nitroglycerine. How safe is it? WebPiroctone Olamine is an antidandruff agent used in antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action. 8600 Rockville Pike It can be used for hair washing, hair care, bath solution, cosmetics, skin care products, and washing products. The concentrations used should be between 0.1 and 1.0 %, depending on the type of finished product. Unauthorized use of these marks is strictly prohibited. It can commonly be found in products like shampoos, cleansers, and hair masks. Malassezia Globosa is not a friendly fungus found in your scalp. Favorite Favorite Similar. Lobjectif de ce travail tait de caractriser les proprits physicochimiques de la piroctone olamine et de mener des tudes de prformulation pour le dveloppement de nouvelles formulations topiques de ce principe actif. 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1). Shampoos with Piroctone Olamine are very effective in curing dandruff and preventing hair loss. This scalp shampoo contains piroctone olamine and climbazole to remove dry dandruff and itchiness. La Roche-Posay La Roche-Posay Toleriane Double Repair Face Moisturizer, SPF 30, 2.5 oz. Statistically significant increases in hair amount were observed by phototrichogram after use of both PO-containing products versus placebo formulations. The mode of action of hydroxypyridone antimycotics is not fully understood. These results illustrate the effectiveness of a cosmetic antioxidant to improve scalp condition thereby improving hair retention. Clinical and Laboratory Standards Intitute (CLSI). Piroctone olamine, also known as Octopirox (OPX) is the monoethanolamine salt of piroctone and is an antifungal agent widely used for the management of dandruff. Piroctone Olamine (Preservative): Cosmetic Ingredient INCI Piroctone Olamine Olamine WebMedicines based on Piroctone Olamine. It is used as a cream or shampoo at a 0.5-1% concentration. This ingredient has anti-fungal properties and appears as a crystalline powder in its raw form that is white or slightly yellow in color. J. J. Thiele, C. Schroeter, S. N. Hsieh, M. Podda, L. Packer, The antioxidant network of the stratum corneum. The difference in fungal growth scoring between the treatment groups (piroctone olamine and amphotericin B) was not statistically significant (P<0.05). Piroctone Olamine has antifungal properties, which will help control the spread of Malassezia globosa. Recommended dosage: 1. WebPicroctone Olamine Piroctone olamine Compositions Boundary Composition(s) open all close all. Reference method for broth dilution testing of yeasts: approved standard-third edition M27-A3. 8600 Rockville Pike Two control wells, free from other fungi and yeasts, were included in the assay. Leal AFG, Leite MC, Medeiros CSQ, Cavalcanti IMF, Wanderley AG, Magalhes NSS, Neves RP. ALCOHOL DENAT.,AQUA (WATER),BUTYLENE GLYCOL,PARFUM (FRAGRANCE),GLYCERIN,MENTHYL LACTATE,PEG-40 HYDROGENATED CASTOR OIL,PIROCTONE OLAMINE,ERUCA SATIVA LEAF EXTRACT,JUGLANS REGIA (WALNUT) SEED EXTRACT,LACTIC ACID,ALPHA-GLUCAN OLIGOSACCHARIDE,BENZOPHENONE-4,VITIS VINIFERA (GRAPE) FRUIT EXTRACT,POLYQUATERNIUM-55,LYSINE CARBOXYMETHYL CYSTEINATE,BAROSMA BETULINA LEAF EXTRACT,LINALOOL,CITRIC ACID,HEXYL CINNAMAL,LACTOCOCCUS FERMENT LYSATE,ETHYLHEXYL METHOXYCINNAMATE,LYSINE THIAZOLIDINE CARBOXYLATE,SODIUM BENZOATE,PHENOXYETHANOL,CAPRYLYL GLYCOL,CARNOSINE,POTASSIUM SORBATE,SODIUM CHLORIDE,BIOSACCHARIDE GUM-4,CAESALPINIA SPINOSA GUM,LINUM USITATISSIMUM (LINSEED) SEED EXTRACT, For the complete and updated list of ingredients, we suggest referring to the product pack. We at Clariant are aware of our responsibility. Payment Way: Bank Transfer, Western Union, Paypal and so on. National Library of Medicine Skin Pharmacol. Ship Time: Within 2~3 working days after you order. Piroctone Olamine and transmitted securely. Octopirox controls the growth of microorganisms effectively and is directly targeting the cause of dandruff.

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